An inappropriate polypharmacy regimen, often the result of cascading negative side effects from an initial opioid, creates a complicated situation for discontiuation. In what sequence should you taper drugs/classifications? What are the pros and cons of medication assisted treatment (MAT) vs. non-MAT tapering? How do you properly address psychosocialspiritual issues and co-morbidities? Proper tapering is complex and individualized. This session helps define best practices.